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The Department of Allergy and Infectious Diseases has an outstanding opportunity for a Research Scientist / Engineer 2 to perform laboratory research work in support of studies on syphilis vaccine discovery and T. pallidum transcriptomics. The overall goal of the research is to find new vaccine candidates for syphilis, and to test existing vaccine candidates in the rabbit model of syphilis.
Expression of recombinant proteins, engineering new vaccine formulations, perform rabbit immunizations and monitoring after infections (30%).
Maintain lab supplies and very detailed lab notebooks (20%).
Development and performance testing of new thermal and kinetic enzymatic assays (10%).
Supervision of work done and training of undergraduate students and technicians joining the lab (20%).
Manage chemical inventories, ensure that the lab is in compliance with EHS standards (10%).
Supervision of work done within the cloning component of al lab members (5%).
Organize lab meetings (5%).
Bachelor's degree in Biology, Biochemistry, Microbiology, Immunology, or related field
Minimum of 2 years’ experience in:
- Molecular biology techniques such as DNA isolation/manipulation, PCR, sequencing, electrophoresis. Western blot, ELISA, cloning, expression of recombinant proteins
- Good sterile technique and the ability to perform tissue culture techniques and maintain cultures.
Willingness to work with animal models (rabbits) and BSL2 organisms.
Ability to prepare reagents, manage data and keep a very detailed notebook.
A high level of motivation, good organizational skills and the ability to work as a member of a team.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
Experience working with Treponema pallidum
Experience working with laboratory rabbits
Conditions of Employment:
Frequent exposure to laboratory animals. Although animal handling requires the use of respirator/mask, people with a known allergy to rabbit fur are discouraged from applying.
As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.
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